Mississippi is one of the easiest long-distance moves from Knoxville: straight down I-40 to Memphis, then south into the Delta, Jackson, and the Gulf Coast. East Tennessee families head south for healthcare, manufacturing, university jobs, and coastal retirement, while Mississippi families move to Knoxville for the mountains and the job market. Buster's Box's Moving runs the corridor in both directions with one dedicated crew and flat-rate pricing.
Memphis is our gateway, and the routes south of it are routes we run weekly. We plan fuel, timing, and the overnight split so delivery lands exactly where promised.
From Oxford and Tupelo to Jackson and the Gulfport beaches, we cover the whole state — including the rural deliveries big van lines avoid.
One clear flat rate before loading day, in writing. No end-of-move surprises when we reach Mississippi.
Drive times, routes, and what to know before you go — city by city.
Route: I-40 W to Memphis, then US-78 E / I-22
The University of Mississippi drives a college-town economy in Oxford, with Tupelo and Corinth adding manufacturing and healthcare nearby.
Route: I-40 W to Memphis, then I-55 S
The state capital: state government, the University of Mississippi Medical Center, and a logistics corridor along I-55 and I-20.
Route: I-40 W to Memphis, I-55 S to I-59 S, then US-49 or I-10
Coastal casinos, shipbuilding, and Keesler Air Force Base anchor the Gulf Coast — a top destination for Tennessee retirees and defense families.
Route: I-40 W to Memphis, I-55 S to I-59 S, then US-49 S
University of Southern Mississippi, Camp Shelby, and a growing healthcare and forestry economy between Jackson and the coast.
Route: I-40 W to Memphis
DeSoto County is one of the fastest-growing areas in the state, drawing Memphis workers who want Mississippi taxes and schools.
Route: I-40 W to Memphis, I-22 E or I-55 S to I-20 E
Naval Air Station Meridian, rail logistics, and a healthcare base on the Alabama line.
Since you are already making an interstate move, we serve the full regional corridor.
New Orleans, Baton Rouge, Shreveport, Lafayette
Birmingham, Mobile, Montgomery, Huntsville
Memphis, Nashville, Chattanooga, Knoxville
Little Rock, Fayetteville, Jonesboro, Fort Smith
Straight answers about routes, timing, and pricing.
Call us at (865) 888-7184 or request a free flat-rate quote online. One dedicated crew, loading to delivery — in both directions.